CDC: New test speeds detection of bird flu in humans

first_imgFeb 3, 2006 (CIDRAP News) – A new test developed by federal experts offers preliminary detection of H5 avian influenza in human patients in about 4 hours, compared with 2 to 3 days for other methods, government officials announced today.”This laboratory test is a major step forward in our ability to more quickly detect cases of H5 avian influenza and provides additional safeguards to protect public health,” Health and Human Services Secretary Mike Leavitt said in a news release.The test is to be used on respiratory samples from patients suspected of having avian flu on the basis of severe illness and possible exposure to sick birds, Dr. Steve Gutman of the Food and Drug Administration’s (FDA’s) Center for Devices and Radiological Health said at a news teleconference this afternoon.The FDA announced its approval of the test, following an unusually quick 2-week review. The test, called the Influenza A/H5 (Asian Lineage) Virus Real-time RT-PCR Primer and Probe Set, was developed by the Centers for Disease Control and Prevention (CDC).Because of the concern that H5N1 avian flu may lead to a human flu pandemic, “FDA acted quickly to evaluate and expedite CDC’s request for approval of this test,” Acting FDA Commissioner Andrew von Eschenbach stated in the news release. He said the rapid review did not compromise the quality of the review process.Gutman said the test yields “a presumptive not a definitive positive.” The test determines only the hemagglutinin (H) type of the virus; further testing is needed to confirm the result and identify the neuraminidase (N) type, officials said.”The test provides preliminary results on suspected H5 influenza samples within four hours once a sample arrives at the lab and testing begins,” the news release states. “Previous testing technology would require at least two to three days to render results.”The CDC will distribute the test to its Laboratory Response Network (LRN), consisting of about 140 labs throughout the country, many of them public health labs, officials said.When LRN labs using the test get positive or equivocal results, they will send the sample to the CDC for confirmatory testing, which will take about 2 to 4 hours once the sample arrives, said Stephan Monroe, acting director of the CDC’s Viral and Rickettsial Diseases Division.Gutman said a negative result from the test does not conclusively rule out the possibility of avian flu. “It’s not intended for general screening of people in the general population; it’s for people with severe respiratory illness who might’ve been exposed to sick birds,” he added.The CDC is sharing the test with the World Health Organization (WHO) and its collaborating labs, which so far have included labs in the United Kingdom, Japan, and Australia, officials said.Concerning use of the test by other labs outside the United States, Monroe said the CDC would distribute the technology only to labs that the CDC judges to have the technical capacity and biosafety measures to use the test properly.The CDC is not charging other labs for the test and is not making money on it, Monroe said. So far the test has been strictly a government-funded project, he said.CDC Director Dr. Julie Gerberding commented in the news release, “The use of this test by laboratories that are part of the LRN, in conjunction with other laboratory testing and clinical observations, may enable earlier detection of influenza cases caused by this specific virus and allow public health agencies to investigate sources of infection and more quickly respond with control and prevention activities.”See also:Feb 3 FDA news releasehttp://archive.hhs.gov/news/press/2006pres/20060203.htmlFeb 3 early release MMWR articlehttp://www.cdc.gov/mmwr/preview/mmwrhtml/mm55e203a1.htm?s_cid=mm55e203a1_elast_img read more

Euro 2016: France 5-2 Iceland: Emphatic Les Bleus thrash brave minnows

first_imgFrance set-up a semi-final clash against Germany by beating fan favourites Iceland 5-2 at the Stade de France.The hosts were well worth their victory having raced into a 4-0 lead at half-time via goals from Olivier Giroud, Paul Pogba, Dimitri Payet and Antoine Griezmann.Although Iceland managed to net twice in the second period – Kolbeinn Sigthorsson and Birkir Bjarnason with the goals – Giroud grabbed his second of the night to secure the most emphatic result of the tournament.Iceland managed some early chances, Sigurdsson firing straight at Lloris and Bodvarsson going down under pressure from Umtiti, with calls for a penalty which was not given.However, Halldorsson had to produce a fine claim to prevent Griezmann tapping Sissoko’s cross into an empty net, and the hosts finally broke through after ramping up the pressure.Matuidi sent a perfectly weighted ball through the heart of the Iceland defence, and Giroud – who was slightly offside – ran onto the pass before sending a first-time finish past Halldorsson into the far corner of the net.The goal settled French nerves, and seven minutes later Pogba netted his first goal of the tournament, converting Griezmann’s corner with a thumping header.Iceland were sitting remarkably deep, and failing to show any of the composure they had in the victory over England in the Round of 16.Chances were few and far between, but Bodvarsson should have pulled one back when Gudmundsson’s throw was sent into the area and flicked on by Sigthorsson; however, the 24-year-old could only lob the loose ball over the bar.France had no trouble dominating the ball, pushing towards goal when they pleased with no fear of being counter-attacked by an Iceland side who were looking tired after just half-an-hour of play.Matuidi volleyed wide from Payet’s cross, before the West Ham star grabbed the third of the night, sending a low left-footed finish into the far corner from the edge of the area.With the half-time whistle just moments away, Iceland would have been pleased for the break, but before they could leave the field, Griezmann broke through on goal and chipped Halldorsson to extend the lead to 4-0.The second half started with France still on top, Griezmann and Payet fluffing chances from the edge of the box, and Pogba sending a low piledriver wide of the post.Iceland did manage a chance – just their second of the game – as the ball broke to Bjarnason on the edge of the D. However, his first time strike ballooned off his foot and flew high and wide of Lloris’ goal.Despite the miss, Iceland seemed to gain confidence from a rare attack, and Sigthorsson pulled a goal back, tapping home Sigurdsson’s right wing cross at the near post.Few suggested the comeback was on, and they were proven right minutes later, as Giroud headed home Payet’s cross to register his third goal of the tournament.Sigurdsson then fired over from inside the box as Iceland got at Les Bleus’ defence, and Lloris pulled off a magnificent save to deny Ingason’s powerful close-range header.The game had reached something of a lull, with the result decided so early on, but Iceland refused to feel sorry for themselves and continued to attack.Sigurdsson had a shot deflected wide, and with six minutes left Bjarnason headed past Lloris to grab a second consolation goal for the brave Iceland side, who bow out of Euro 2016 having earned a number of plaudits following displays of spirit, hard work, and tactical excellence. Antoine Griezmann celebrates his majestic goal 1last_img read more